Aspergillus-mediated allergic airway inflammation is triggered by dendritic cell recognition of a defined spore morphotype.

Publicity to fungi, particularly Aspergillus fumigatus (A.f.), can elicit potent allergic irritation that triggers and worsens asthmatic illness. Dendritic cells (DCs), provoke allergic inflammatory responses to allergic stimuli. Nevertheless, it’s unclear if A.f. spores throughout isotropic progress (early spore swelling) can activate DCs to provoke allergic responses or if germination is required. This lack of primary understanding of how A.f. causes illness is a barrier to the event of latest remedies.

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