Publicity to environmental allergens, similar to home mud mite (HDM), are implicated in improvement of bronchial asthma and allergic airway ailments. Transcription components Blimp-1 (encoded by Prdm1 gene) and Bcl-6 are necessary for differentiation of CD4+ T cells. The objective of this challenge was to elucidate the roles of Blimp-1 and Bcl-6 in allergic immune responses by utilizing mouse fashions.
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