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Transcription Factors Blimp-1 and Bcl-6 Regulate Distinct Phenotypes of Allergic Immune Responses to House Dust Mite in Mice

Publicity to environmental allergens, similar to home mud mite (HDM), are implicated in improvement of bronchial asthma and allergic airway ailments. Transcription components Blimp-1 (encoded by Prdm1 gene) and Bcl-6 are necessary for differentiation of CD4+ T cells. The objective of this challenge was to elucidate the roles of Blimp-1 and Bcl-6 in allergic immune responses by utilizing mouse fashions.

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