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The Editors’ Choice

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Remedy choices for itch are restricted. Antihistamines signify probably the most extensively obtainable class of antipruritic medicine, with over $2 billion in gross sales per yr for itch alone. Nonetheless, antihistamines exhibit poor efficacy in most persistent itch circumstances, even these related to the histaminergic itch pathway like urticaria. Thus, itch is commonly categorised dichotomously as both histaminergic or nonhistaminergic in nature. On this situation, Trier et al (p 852) present proof that means that this canonical distinction is probably going overly simplistic.

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