Power hand eczema (CHE) is a typical, heterogenous pores and skin illness with etiological subtypes together with atopic dermatitis (AD), allergic contact dermatitis, and irritant contact dermatitis. Nonetheless, little is thought in regards to the molecular patterns of CHE throughout its subtypes, thereby limiting the event of focused remedies. On this difficulty, Quaade et al (p 1250) report their investigation of the CHE transcriptome, conducting bulk RNA-sequencing of 220 pores and skin biopsies collected from palm, dorsal hand, and arm pores and skin of 96 sufferers with CHE with or with out AD and 32 wholesome people.
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