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Ruxolitinib Treatment Ameliorates Clinical, Immunological, and Transcriptomic Aberrations in Patients with STAT3 Gain-of-Function Disease
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STAT3 gain-of-function (GOF) illness presents with lymphoproliferation, autoimmunity, and failure to thrive. Whereas JAK inhibitors have alleviated signs, their results on illness pathogenesis stay unclear.
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