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I thank Dupont et al1 for his or her correspondence on my Paradigms and Views article. The important thing factors raised by Dupont et al1 focus on 3 points: (1) the existence of references supporting my assertion that lower than 1% of peanut protein is more likely to be delivered into the pores and skin from a Viaskin patch, (2) their declare that the “majority” of proteins from a Viaskin patch are absorbed into the human pores and skin, and (3) whether or not an estimate of the Viaskin patch dose that enters the pores and skin can be utilized to estimate the dose for a microneedle allergen immunotherapy therapy.

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