The KIT D816V mutation is a trademark of clonal mast cell illness (cMCD) together with systemic mastocytosis. cMCD prognosis is incessantly delayed resulting from variable signs till confirmatory bone marrow biopsy is carried out. Screening strategies for KIT D816V variant in peripheral blood (PB) might facilitate prognosis. Prevalence of KIT D816V in sufferers with anaphylaxis or mast cell activation (MCA) signs is unknown.
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