Precision Medicine for Asthma Treatment: Unlocking the Potential of the Epigenome and Microbiome

Bronchial asthma is a number one worldwide biomedical concern. Sufferers can expertise life-threatening worsening episodes (exacerbations) often managed by anti-inflammatory and bronchodilator medication. Nevertheless, substantial heterogeneity in remedy response exists and a subset of sufferers with unresolved bronchial asthma carry the key burden of this illness. The examine of the epigenome and microbiome would possibly bridge the hole between human genetics and environmental exposures to partially clarify the heterogeneity in drug response.

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