News beyond our pages – March 2025

Regardless of important charges of antagonistic occasions and remedy failure, systemic glucocorticoids are generally used to deal with bronchial asthma and persistent obstructive pulmonary illness (COPD) exacerbations. Ramakrishnan et al (Lancet Respir Med 2024 Nov 27; https://doi.org/10.1016/S2213-2600(24)00299-6) carried out a randomized, placebo-controlled part 2 trial (ABRA) to look at the security and efficacy of benralizumab, which blocks IL-5 receptor-α, in treating acute eosinophilic exacerbations of bronchial asthma and COPD. Topics with blood eosinophil counts of at the very least 300 cells per μL on the time of exacerbation had been randomized to three remedy teams

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