News beyond our pages – August 2024

Whereas a number of immune cell subsets have been implicated within the pathogenesis of continual obstructive pulmonary illness (COPD), their underlying mobile interactions stay incompletely understood. Subsequently, Jia et al (Am J Respir Crit Care Med 2024 Mar 27; https://doi.org/10.1164/rccm.202303-0442OC) utilized cutting-edge single-cell and imaging mass cytometry strategies to comprehensively characterize the modifications within the alveolar immune cell compartment in extreme (stage III or IV) COPD. Larger percentages of each central reminiscence CD4+ and CD8+ T cells have been noticed in alveolar tissue from sufferers with extreme COPD as in comparison with management people.

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