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The SOLAR II examine by Sadatsafavi et al (Am J Respir Crit Care Med 2025;211:1165-74; https://doi.org/10.1164/rccm.202501-0246OC) exhibits that biologic initiators had 18% decrease threat of growing any oral corticosteroid (OCS)-related opposed consequence in comparison with noninitiators, primarily pushed by the decreased threat of growing diabetes (by 38%), main opposed cardiovascular occasions (MACE) (by 35%), and nervousness/despair (by 32%). The magnitude of charge discount was similar to these proven by accessible disease-specific brokers for MACE and diabetes.

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