Multi-Compartment Biomarker Profiling in Aspirin Exacerbated Respiratory Disease On Aspirin Therapy After Desensitization

Aspirin-exacerbated respiratory illness (AERD) is characterised by a medical triad of bronchial asthma, aspirin hypersensitivity, and persistent rhinosinusitis with nasal polyps (CRSwNP), together with an imbalance between proinflammatory and anti inflammatory eicosanoids. This examine aimed to characterize the medical, immunological, and transcriptomic profiles of AERD utilizing induced sputum (IS), nasal lavage (NL), and blood biomarkers at baseline and through the aspirin remedy after desensitization (ATAD).

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