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Mast Cell Activation Syndrome: current understanding and research needs

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Mast cell activation syndrome (MCAS) is a time period utilized to a number of medical entities which have gained elevated consideration from sufferers and medical suppliers. Whereas a number of descriptive publications about MCAS exist, there are lots of gaps in information leading to confusion about this medical syndrome. Whether or not MCAS is a major syndrome or exists as a constellation of signs within the context of identified inflammatory, allergic, or clonal problems related to systemic mast cell (MC) activation just isn’t properly understood.

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