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Lactylation-driven ALKBH5 diminishes macrophage NLRP3 inflammasome activation in patients with G6PT deficiency

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Neutropenia represents an necessary scientific downside in sufferers with glycogen storage illness kind Ib (GSD-Ib), characterised by genetic deficiency in glucose-6-phosphate translocase (G6PT/SLC37A4). Nevertheless, the position of G6PT in macrophages has not been elucidated.

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