Dipeptidyl peptidase-1 (DPP-1/Cathepsin C) processes and prompts neutrophil serine proteases. Brensocatib (an oral, reversible, aggressive DPP-1 inhibitor) is a novel remedy for bronchiectasis beforehand proven to scale back sputum protease exercise and forestall exacerbations. Broader results of DPP-1 inhibition on the immune response haven’t been investigated.
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