📖 Desk of Contents
As we age, reminiscence and mind well being turn out to be greater considerations. This has led to a rising curiosity in dietary supplements like Prevagen, which is marketed to enhance reminiscence and assist mind perform. Its predominant ingredient, Apoaequorin, comes from jellyfish and is claimed to assist with age-related reminiscence points.
However how does Prevagen actually work? Are the components as efficient because the claims recommend? On this weblog, we’ll have a look at what’s inside Prevagen, the way it works, the totally different variations out there, and a few well-liked alternate options.
What Is Prevagen?
Prevagen is a well-liked reminiscence complement that claims to enhance mind perform, particularly for folks experiencing age-related reminiscence loss. It’s typically present in pharmacies and well being shops, marketed as a easy answer for reinforcing reminiscence and supporting total mind well being.†
Its key ingredient, Apoaequorin, units Prevagen other than different reminiscence dietary supplements. This protein was initially found in jellyfish and is believed to assist regulate calcium ranges in mind cells, which is assumed to play a job in sustaining wholesome mind perform.†
Prevagen is available in totally different types, together with common energy, further energy, and chewables, providing choices for varied wants. Whereas many customers report advantages, the complement has additionally confronted criticism, with some questioning its effectiveness. Earlier than diving deeper into the way it works, let’s take a more in-depth have a look at its components.†
Prevagen Substances:
Prevagen incorporates just a few key components that contribute to its claims of supporting reminiscence and cognitive perform. Let’s break down these components to grasp what they’re and the way they may work:
1. Apoaequorin:
- What It Is: Apoaequorin is a calcium-binding protein initially derived from the jellyfish Aequorea victoria. (1)
- How It Works: Apoaequorin is assumed to assist regulate calcium ranges in mind cells. Correct calcium regulation is crucial for sustaining neuron well being and performance. Some research recommend it might assist cognitive perform and assist scale back age-related reminiscence decline. (1,2)
2. Vitamin D:
- What It Is: Some variations of Prevagen embody Vitamin D, a significant nutrient that performs varied roles within the physique, together with supporting mind well being. (3)
- How It Works: Vitamin D is thought to be concerned in neuroprotection and should assist total cognitive perform. It helps preserve wholesome mind cells and may regulate temper, which is crucial for psychological readability. (3,4)
3. Different Substances:
- Inactive Substances: Prevagen additionally incorporates varied inactive components, equivalent to microcrystalline cellulose, silica, and magnesium stearate, which function binders, fillers, or stabilizers to assist kind the pill or capsule.†
These components mix to create a complement to boost reminiscence and cognitive well being. Nevertheless, whereas the theoretical advantages sound promising, it’s important to contemplate the scientific proof supporting these claims. Subsequent, we’ll discover how Apoaequorin is meant to work and what the analysis says about its effectiveness.†
How Is Apoaequorin Purported to Work?
Apoaequorin, the first ingredient in Prevagen, is touted for its potential advantages in supporting reminiscence and cognitive perform. Right here’s a more in-depth have a look at the way it’s believed to work:
1. Calcium Regulation:
- Position of Calcium in Mind Well being: Calcium is crucial for varied mobile processes within the mind, together with neurotransmitter launch, neuron communication, and total cell well being. Nevertheless, an imbalance in calcium ranges can result in points equivalent to cell harm and impaired cognitive perform. (5,6)
- Apoaequorin’s Perform: Apoaequorin is designed to bind to calcium within the mind. Regulating calcium ranges might assist defend mind cells from harm and assist their correct functioning. This might probably improve communication between neurons, main to raised reminiscence and cognitive efficiency.†
2. Neuroprotection:
- Defending Mind Cells: Analysis means that Apoaequorin might have neuroprotective properties, which may assist safeguard mind cells in opposition to stress and harm from getting older and environmental toxins. (2)
- Decreasing Oxidative Stress: Oxidative stress can hurt mind cells and contribute to cognitive decline. By regulating calcium and supporting total cell well being, Apoaequorin might assist scale back the results of oxidative stress. (7)
3. Enhancing Cognitive Perform:
- Supporting Reminiscence: By sustaining wholesome calcium ranges and defending mind cells, Apoaequorin goals to enhance varied elements of cognitive perform, together with reminiscence, focus, and psychological readability. (8)
- Concentrating on Age-Associated Decline: Most of the claims surrounding Apoaequorin give attention to its potential to counteract age-related cognitive decline, making it interesting to older adults trying to preserve their psychological sharpness. (8)
Whereas these mechanisms sound promising, it’s important to notice that the scientific proof supporting these claims remains to be evolving.†
🧩 What to Anticipate When Taking Prevagen
- Timeline: Some customers report noticing gentle enhancements in recall, psychological readability, or word-finding means inside 4–8 weeks. Others might not discover important adjustments.†
- Finest outcomes: Doubtless achieved when mixed with life-style habits that assist mind well being, equivalent to common train, high quality sleep, social engagement, and a nutrient-rich weight-reduction plan.†
- Limitations: Outcomes fluctuate extensively. Not all customers expertise measurable enhancements, and the prevailing scientific proof is modest.†
❓Widespread Client Questions
Q: Is Prevagen FDA-approved?
A: No. As a dietary complement, Prevagen just isn’t FDA-approved to deal with, stop, or remedy any illness.†
Q: Can I take Prevagen with different dietary supplements?
A: Usually, sure—particularly with multivitamins or omega-3 dietary supplements—however seek the advice of a healthcare supplier to keep away from ingredient overlaps or drug interactions.†
Q: How does Prevagen examine to prescription reminiscence medication?
A: Prevagen is a complement, not a drug. Prescription choices for dementia or Alzheimer’s illness (e.g., donepezil) are FDA-approved for particular makes use of, whereas Prevagen’s claims are based mostly on dietary complement laws.†
Completely different Variations:
Prevagen is available in a number of formulations, every designed to cater to totally different preferences and wishes.
Right here’s an summary of the out there variations and their distinctive options:
| Dosage | Goal Viewers | Utilization | |
| Prevagen Common Energy | 10 mg of Apoaequorin. | This model is appropriate for people searching for fundamental assist for reminiscence and cognitive perform, particularly older adults experiencing gentle reminiscence points.† | Really helpful for each day use, usually one pill per day, to assist total mind well being.† |
| Prevagen Additional Energy | 20 mg of Apoaequorin | Designed for individuals who may have a better dosage for extra pronounced cognitive assist or those that haven’t seen adequate advantages from the common energy formulation.† | Much like the common energy, it’s taken as soon as each day however might present an enhanced impact for customers searching for extra sturdy assist.† |
| Prevagen Chewables | 10 mg of Apoaequorin. | Best for people preferring a extra handy and attractive possibility. This formulation is especially well-liked amongst those that have problem swallowing drugs.† | These might be taken as soon as each day, offering an pleasing approach to incorporate the complement right into a each day routine.† |
| Prevagen Skilled | ~30 mg of Apoaequorin. | This model is usually marketed to healthcare professionals and could also be advisable for people with extra important cognitive considerations.† | Really helpful by healthcare suppliers for focused cognitive assist, although it might not be as extensively out there as the opposite variations.† |
How Does Prevagen Evaluate?
Right here, we’ll examine Prevagen to some well-liked alternate options, their key components, advantages, and total effectiveness.
1. Ginkgo Biloba:
Derived from the Ginkgo tree, Ginkgo Biloba is famend for its function in enhancing blood circulation, notably to the mind. Its means to extend oxygen and nutrient supply to mind cells makes it a well-liked alternative for cognitive assist. (9)
Advantages:
- Reminiscence Enhancement: Ginkgo biloba might assist enhance reminiscence and cognitive perform, notably in older adults. Some research recommend it might be helpful for these with age-related cognitive decline. (9)
- Psychological Readability and Focus: Customers typically report improved focus and psychological readability, enhancing total cognitive efficiency. (10)
- Antioxidant Safety: Ginkgo biloba’s antioxidants might assist defend mind cells from oxidative stress, which may contribute to cognitive decline and neurodegenerative illnesses. (11)
Comparability:
Whereas Prevagen (Apoaequorin) targets calcium regulation in mind cells, supporting neuronal well being, Ginkgo Biloba enhances blood circulation to enhance oxygen and nutrient provide to mind cells. Prevagen might present extra focused assist for reminiscence loss associated to getting older, whereas Ginkgo Biloba gives broader cognitive advantages by improved circulation and antioxidant safety.†
2. Choline:
Choline is a essential nutrient typically categorized with B nutritional vitamins. It performs an important function in mind well being, liver perform, and muscle management by supporting the manufacturing of acetylcholine, a neurotransmitter very important for reminiscence and studying. (12)
Advantages:
- Reminiscence and Studying: Choline is crucial for producing acetylcholine, which is essential for reminiscence formation and studying. Supplementing with choline might improve reminiscence retention and cognitive efficiency, particularly in duties requiring focus and focus. (12,13)
- Mind Growth: Sufficient choline consumption is important throughout being pregnant and early childhood, because it helps mind improvement and should affect cognitive perform all through life. (14)
Comparability:
Prevagen’s Apoaequorin helps neuronal well being by calcium regulation, whereas choline instantly boosts acetylcholine ranges, a neurotransmitter that performs a basic function in studying and reminiscence. This makes choline notably efficient for these searching for enhanced cognitive processing, reminiscence retention, and psychological readability.†
3. Phosphatidylserine:
Phosphatidylserine (PS) is a phospholipid present in excessive concentrations in mind cell membranes, important for sustaining cell construction and performance. It performs a essential function in reminiscence, temper regulation, and stress response. However extra importantly, Phosphatidylserine has scientific analysis indicating it could enhance reminiscence and cognition in older people with reminiscence complaints. It’s really an ingredient in a few of the different merchandise we mentioned (like Cognitex and Neuriva). In case you’re searching for confirmed reminiscence assist, PS is likely one of the few dietary supplements with credible human research behind it. (15,16)
Advantages:
- Reminiscence Enhancement: Analysis suggests phosphatidylserine can enhance reminiscence and cognitive efficiency, notably in older adults. It could be helpful for these experiencing age-related cognitive decline. (17)
- Stress Discount: Some research point out phosphatidylserine might assist scale back cortisol ranges, the hormone launched throughout stress. Decreasing cortisol can result in improved temper and cognitive perform. (18)
- Enhanced Focus: Phosphatidylserine might assist enhance focus and focus by supporting neurotransmitter perform and neuronal well being, making it an excellent possibility for college students and professionals alike. (15,16)
Comparability:
Prevagen helps cognitive well being by regulating calcium ranges inside neurons, whereas phosphatidylserine strengthens mind cell membranes and promotes neurotransmitter exercise. This makes PS notably efficient in enhancing reminiscence, focus, and stress resilience, making it a complementary or different possibility for these trying to improve mind perform.†
4. Bacopa Monnieri:
Bacopa Monnieri is a potent herb utilized in conventional Ayurvedic drugs for its cognitive-enhancing and neuroprotective properties. Recognized for enhancing reminiscence and lowering nervousness, Bacopa is extensively utilized in nootropic dietary supplements. (18)
Advantages:
- Cognitive Enhancement: Analysis means that Bacopa Monnieri might enhance reminiscence, consideration, and total cognitive efficiency, notably in duties requiring studying and recall. Common use might result in enhanced psychological readability and focus. (18)
- Stress and Anxiousness Discount: Bacopa has been proven to have adaptogenic properties, which can assist scale back stress and nervousness ranges. By assuaging stress, Bacopa can enhance total psychological well-being and cognitive perform. (19)
- Neuroprotection: Bacopa’s antioxidant properties might assist defend neurons from oxidative harm, probably lowering the danger of age-related cognitive decline. (20)
Comparability:
Whereas Prevagen targets neuronal well being by calcium regulation, Bacopa Monnieri enhances cognitive efficiency by its bacosides, which assist neurotransmitter signaling and neuronal restore. Bacopa might supply broader advantages, together with stress reduction and reminiscence enhancement, making it a gorgeous possibility for holistic cognitive assist.†
5. Lion’s Mane Mushroom:
Lion’s Mane Mushroom is a pure nootropic recognized for its neuroprotective results and its means to stimulate the manufacturing of Nerve Progress Issue (NGF), which is important for neuron well being and performance. (21)
Advantages:
- Cognitive Enhancement: Analysis means that Lion’s Mane might enhance cognitive perform, reminiscence, and focus. Customers typically report elevated psychological readability and enhanced studying capabilities. (22)
- Neuroprotection: The power of Lion’s Mane to advertise NGF manufacturing might assist defend mind cells from oxidative stress and degeneration, lowering the danger of cognitive decline as people age. (21)
- Temper and Anxiousness Help: Some research point out that Lion’s Mane may assist alleviate signs of tension and melancholy, contributing to improved total psychological well-being. (22,23)
Comparability:
Prevagen helps mind well being by calcium stability, whereas Lion’s Mane encourages neurogenesis by NGF manufacturing, supporting mind cell development and connectivity. Lion’s Mane is especially efficient for these trying to improve psychological readability, reminiscence, and temper, making it a powerful pure different.†
6. PQQ (Pyrroloquinoline Quinone):
PQQ is a potent antioxidant that helps mitochondrial perform and neuroprotection. It’s typically utilized in mind well being dietary supplements for its means to advertise vitality manufacturing in cells and defend in opposition to oxidative harm. (24)
Advantages:
- Cognitive Enhancement: Analysis means that PQQ might enhance cognitive perform, reminiscence, and total mind efficiency. Customers typically report elevated psychological readability and higher focus. (25)
- Neuroprotection: PQQ’s antioxidant properties assist defend neurons from oxidative stress and harm, probably lowering the danger of cognitive decline. (26)
- Power Help: By selling mitochondrial perform, PQQ might improve total vitality ranges within the mind, contributing to improved psychological efficiency. (27)
Comparability:
Prevagen focuses on calcium regulation inside neurons, whereas PQQ helps mitochondrial well being, providing sturdy safety in opposition to oxidative stress and enhancing vitality manufacturing. PQQ is a wonderful alternative for these trying to improve cognitive perform by improved mobile vitality and safety.†
Standard Merchandise:
On this part, we’ll discover a few of the hottest reminiscence and cognitive-enhancement dietary supplements out there immediately. These merchandise mix scientifically-backed components to assist mind well being, enhancing focus, and enhancing reminiscence†
Life Extension Cognitex Alpha GPC:
Life Extension Cognitex Alpha GPC is formulated to assist cognitive perform and reminiscence. One in all its standout components is Alpha-GPC, a choline compound recognized to cross the blood-brain barrier and improve acetylcholine manufacturing. Acetylcholine is a neurotransmitter that performs a essential function in reminiscence formation, studying, and muscle coordination.†
Moreover, phosphatidylserine, one other key ingredient, is a phospholipid that contributes to cell membrane integrity and signaling throughout the mind. It helps neurotransmitter exercise and has been proven to boost cognitive perform, particularly in getting older people.†
The inclusion of untamed blueberry extract provides an antioxidant ingredient, serving to defend mind cells from oxidative harm, which is related to cognitive decline. This highly effective mixture helps each quick mind perform and long-term cognitive well being.†
Advantages:
- Enhances reminiscence formation and recall†
- Protects mind cells from oxidative stress†
- Helps wholesome acetylcholine ranges for studying and focus†
- Could scale back the danger of age-related cognitive decline†
How Does It Evaluate? In comparison with Prevagen, which focuses on calcium regulation and neuronal safety, Cognitex Alpha GPC emphasizes neurotransmitter assist by choline and phosphatidylserine. This makes it a powerful alternative for these trying to enhance focus, reminiscence, and total mind perform, notably in older adults or these experiencing cognitive decline.†
How To Take Life Extension Cognitex Alpha GPC:
The producer recommends taking one (1) softgel each day or as a healthcare practitioner recommends.
Onnit Alpha Brain:
Onnit Alpha Mind is likely one of the hottest cognitive-enhancement dietary supplements out there, recognized for its mix of pure nootropic components that improve mind efficiency. The Onnit Movement Mix consists of L-Tyrosine and L-Theanine, which assist scale back stress and promote a peaceful, targeted state with out drowsiness. This mix additionally consists of phosphatidylserine, which, as talked about earlier, helps cell membrane integrity and mind perform.†
The Onnit Focus Mix gives Alpha-GPC for acetylcholine manufacturing, together with Bacopa Monnieri for its memory-enhancing and neuroprotective properties. Huperzia Serrata provides one other layer of assist by inhibiting the breakdown of acetylcholine, permitting for longer-lasting cognitive advantages.†
Cat’s Claw Extract, recognized for its neuroprotective and anti inflammatory properties, helps protect the mind from environmental stressors whereas selling psychological readability.†
Advantages:
- Improves reminiscence and cognitive processing†
- Enhances focus and psychological readability†
- Reduces stress whereas selling leisure†
- Protects in opposition to neurodegenerative harm†
How Does It Evaluate? Whereas Prevagen focuses on calcium regulation within the mind, Alpha Mind targets cognitive enhancement by a holistic mix that helps acetylcholine manufacturing and psychological readability. It’s ideally suited for customers searching for each stress reduction and improved focus. Alpha Mind could also be higher for youthful adults or these coping with high-stress environments, whereas Prevagen could also be extra suited to people experiencing age-related cognitive decline.†
How To Take Onnit Alpha Mind:
The producer recommends taking two capsules each day, ideally with a lightweight meal.
Condemned Labz MSTRMND:
Condemned Labz MSTRMND is designed for people searching for a complete cognitive enhance. What units it aside is the mixture of conventional nootropic components with energy-boosting components. Lion’s Mane and CognatiQ are included for his or her function in selling neurogenesis, which is the expansion and restore of neurons. This helps long-term cognitive well being and enhances psychological flexibility.
Choline Bitartrate will increase acetylcholine ranges, enhancing reminiscence and focus, whereas Noopept, a potent nootropic, promotes cognitive readability and studying retention. The twin caffeine sources—caffeine Anhydrous and Infinergy—present sustained vitality with out the everyday crash, making MSTRMND an important alternative for people needing to keep up psychological sharpness all through the day.
Mucuna Pruriens, a pure supply of L-Dopa, helps stimulate dopamine manufacturing, enhancing temper and motivation, important for productiveness and studying.
Advantages:
- Promotes the expansion and restore of neurons for long-term mind well being†
- Enhances reminiscence, studying, and cognitive readability†
- Offers sustained vitality with out crashes†
- Boosts temper and motivation†
How Does It Evaluate? MSTRMND gives a robust mix of cognitive enhancers and vitality assist, making it ideally suited for people who wish to preserve excessive productiveness and psychological sharpness all through the day. In comparison with Prevagen, which is extra targeted on calcium stability within the mind for cognitive assist, MSTRMND gives quick vitality and focus-boosting results alongside long-term mind well being advantages.†
How To Take Condemned Labz MSTRMND:
The producer recommends taking two (2) capsules with meals half-hour earlier than participating in something that calls for consideration to assist assist reminiscence, cognition and focus.†
Magnum Nutraceuticals Mane Brain:
Magnum Nutraceuticals Mane Mind combines a number of well-researched nootropic components to spice up reminiscence, focus, and total mind perform. The star ingredient, Lion’s Mane Mushroom, is thought for selling neurogenesis and defending in opposition to neurodegenerative illnesses.†
The components additionally consists of N-Acetyl L-Tyrosine, which helps handle stress by supporting neurotransmitter manufacturing, notably dopamine and norepinephrine. This helps customers preserve focus and calm in hectic conditions.†
Bacopa Monnieri is used for its cognitive-enhancing properties, enhancing reminiscence retention and psychological readability. L-Theanine contributes to a peaceful, targeted state with out inflicting drowsiness, making it ideally suited for people who want to remain alert however relaxed.
Lastly, Alpha-GPC and Huperzine Serrata are included to assist acetylcholine ranges, making certain that reminiscence and studying processes stay sharp and efficient.†
Advantages:
- Enhances neurogenesis and mind cell safety†
- Helps reminiscence retention and studying†
- Reduces stress whereas selling focus†
- Improves temper and cognitive perform†
How Does It Evaluate? Whereas Prevagen helps mind perform by calcium regulation, Mane Mind focuses on enhancing neurotransmitter ranges and neurogenesis. It is a wonderful possibility for these searching for a pure means to enhance focus and reminiscence, notably underneath stress, making it a strong alternative for college students or professionals.†
How To Take Magnum Nutraceuticals Mane Mind:
The producer recommends taking 2 capsules each day. Keep away from taking it at bedtime.
Which Ought to You Strive:
Choosing the proper cognitive complement is dependent upon your particular targets and life-style wants. Let’s break down who would possibly profit most from every product talked about.
Life Extension Cognitex Alpha GPC:
- Finest For: Individuals searching for long-term mind well being and reminiscence assist.†
- Why: This components is a good match in the event you give attention to defending your mind from getting older or oxidative stress. With Alpha GPC and phosphatidylserine supporting cell membranes and neurotransmitter exercise, and wild blueberry extract providing antioxidant safety, Cognitex is good for these involved with total mind well being and reminiscence preservation over time.†
Onnit Alpha Brain:
- Finest For: People who need an all-around cognitive enhance, emphasizing focus and psychological readability.†
- Why: Alpha Mind blends Alpha GPC, Bacopa Monnieri, and Huperzine A to boost reminiscence and studying whereas including L-Theanine and L-Tyrosine to assist handle stress and improve focus. Cat’s Claw brings neuroprotective advantages, making this product a good selection for these searching for improved consideration and long-term mind well being. Its big selection of components makes it versatile for varied cognitive wants.†
Condemned Labz MSTRMND:
- Finest For: Excessive-energy people, avid gamers, or professionals who want a cognitive enhance mixed with sustained vitality.†
- Why: If you need a psychological edge paired with bodily vitality, MSTRMND stands out. It blends cognitive enhancers like Lion’s Mane and Choline Bitartrate for reminiscence and focus alongside caffeine and Infinergy to spice up vitality. CognatiQ helps neurogenesis, whereas Mucuna Pruriens enhances temper and motivation, making this an excellent possibility for these needing psychological readability and vitality all through the day.†
Magnum Nutraceuticals Mane Brain:
- Finest For: Individuals searching for a stability between cognitive enhancement and stress discount.†
- Why: Lion’s Mane and Bacopa Monnieri are robust nootropics for supporting neurogenesis and reminiscence, whereas L-Theanine and N-Acetyl L-Tyrosine work to handle stress and promote calm focus. Alpha GPC and Huperzine A additionally enhance neurotransmitter exercise for enhanced reminiscence and studying. This product is good for people who must focus and handle stress concurrently, like college students or professionals balancing heavy workloads.†
Is Prevagen Price It?
Present scientific proof doesn’t strongly assist Prevagen as an efficient reminiscence booster. The complement’s predominant ingredient has not proven important advantages in well-designed research in comparison with a placebo. The one scientific trial by Prevagen’s producer reported some enhancements, however consultants have questioned these findings as a result of the variations had been minimal and the research had methodological points.†
In actual fact, in late 2024, a U.S. courtroom discovered Prevagen’s reminiscence enchancment claims to be unproven, and the corporate can now not promote Prevagen as a reminiscence enhancer. Even so, some people really feel it helps them, which could possibly be on account of a placebo impact or very gentle advantages. Everyone seems to be totally different, however total, Prevagen shouldn’t be seen as a assured answer for reminiscence points. (28)
The place to Purchase Reminiscence Complement?
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Wrapping Up!
And this marks the tip of our publish on Prevagen. Thanks for studying! And as all the time, if there’s one thing unclear, you’ve gotten one other query, or you’ve gotten one other concept for a weblog, email us!
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Warnings And Facet Results:
Most individuals don’t expertise critical unwanted effects; the truth is, no critical antagonistic occasions have been instantly attributed to Prevagen in trials. Nevertheless it’s necessary to pay attention to these doable gentle results and cease utilizing it in the event you discover any issues. Moreover, Prevagen just isn’t a therapy for dementia or Alzheimer’s – in the event you suspect you’ve gotten greater than regular forgetfulness, see a healthcare supplier. And as with every complement, those that are pregnant, nursing, underneath 18, or on drugs ought to seek the advice of a physician earlier than use.
Disclaimer:
†PLEASE NOTE: The intention of the knowledge offered is for reference solely. Moreover, we’re by no means offering medical recommendation or instruction. As a substitute, the knowledge offered on this information/weblog makes use of anecdotal info and out there research/evaluations. Whereas our aim is to keep up and show correct info, we will’t assure it represents the most recent formulation of the product or info. Subsequently, please go to the producer’s web site when you have any considerations. Additionally, the knowledge above doesn’t signify our views right here at Identical Day Dietary supplements. As a substitute, these are the producers’ and customers’ views and data. The Meals and Drug Administration has not evaluated these statements. Lastly, these merchandise intention to not diagnose, deal with, remedy, or stop any illness or sickness.
