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Estimation of serum tryptase reference intervals via an indirect method reveal age- and sex-dependent upper limits

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Tryptase is a mast cell (MC)-specific protease that may be measured in serum by utilizing immunoassays. Serum tryptase focus correlates with MC activation and mobile burden, which allows its use as a biomarker within the analysis of allergic reactions, activation issues, and indolent systemic mastocytosis (SM).1,2

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