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Home » Blog » Early bone marrow alterations in patients with adenosine deaminase 2 deficiency across disease phenotypes and severities

Early bone marrow alterations in patients with adenosine deaminase 2 deficiency across disease phenotypes and severities

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Deficiency of adenosine deaminase 2 (DADA2) is a posh monogenic illness attributable to recessive mutations within the ADA2 gene. DADA2 displays a broad medical spectrum encompassing vasculitis, immunodeficiency, and hematological abnormalities. But, the impression of DADA2 on the bone marrow (BM) microenvironment is basically unexplored.

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