Sufferers with extreme bronchial asthma can current with eosinophilic kind 2 (T2), neutrophilic, or blended irritation that drives airway reworking and exacerbations and represents a significant remedy problem. The frequent β (βc) receptor alerts for 3 cytokines, GM-CSF, IL-5, and IL-3, which collectively mediate T2 and neutrophilic irritation.
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