Meals allergy is a rising drawback with restricted remedy choices. It is very important perceive the mechanisms of meals tolerance and allergy to advertise the event of directed therapies. Dendritic cells are specialised antigen presenting cells that prime adaptive immune responses, akin to these concerned within the improvement of oral tolerance and meals allergic reactions. The dendritic cell subsets within the intestine and pores and skin are outlined by their floor markers and performance. The default response to an ingested innocuous antigen is oral tolerance, which requires both intestine dendritic cells or a subset of newly recognized RORγt+ antigen presenting cells to induce the event of intestine peripheral T regulatory cells.
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