What Is Histamine Intolerance | What Is DAO (Diamine Oxidase) | How DAO Supplements Work | Who Might Benefit | What to Look For | Other Ways to Support Histamine Balance | Where To Buy | Wrapping Up | Warnings And Side Effects |Disclaimer
Ever discover complications, hives, or digestive points after consuming meals like aged cheese, wine, or fermented snacks? You is likely to be coping with one thing known as histamine intolerance—a situation the place your physique struggles to interrupt down histamine correctly. One of many key gamers on this course of is an enzyme known as diamine oxidase, or DAO. When DAO ranges are low, histamine can construct up and set off a spread of uncomfortable signs. That’s the place DAO dietary supplements are available in. On this submit, we’ll break down what DAO is, the way it works, and why a complement is likely to be price contemplating if histamine is wreaking havoc in your day.
What Is Histamine Intolerance?
Histamine intolerance isn’t an allergy—it’s extra like a visitors jam. Histamine is a pure compound present in your physique and in lots of meals. It performs a task in immune responses, digestion, and even acts as a neurotransmitter. However when an excessive amount of histamine builds up and your physique can’t break it down quick sufficient, that’s when issues begin. (1,2)
This buildup can set off a variety of signs, together with:
- Complications or migraines†
- Pores and skin flushing or hives†
- Nasal congestion or sneezing†
- Digestive points like bloating, gasoline, or cramps†
- Irregular menstrual cycles†
- Anxiousness or dizziness†
Not like meals allergic reactions, which contain the immune system, histamine intolerance is about enzymatic imbalance—particularly, an absence or deficiency of the enzyme that breaks histamine down in your digestive tract. That enzyme is DAO (diamine oxidase), and when it’s not doing its job effectively, histamine can accumulate and trigger signs that mimic allergic reactions or meals sensitivities. (1,2)
Briefly: it’s not what you’re consuming, it’s what your physique can’t course of correctly.†
What Is DAO (Diamine Oxidase)?
DAO, brief for diamine oxidase, is an enzyme your physique produces to assist break down histamine—particularly, the histamine discovered within the meals you eat. Consider DAO as your physique’s pure protection towards histamine overload. It’s primarily produced within the lining of your small gut, in addition to within the kidneys and thymus, and its job is to forestall extra histamine from getting into your bloodstream by way of digestion. (1,2,3)
Right here’s the catch: in case your physique doesn’t make sufficient DAO, or if the enzyme isn’t working effectively, histamine can construct up and set off signs of histamine intolerance. †
A number of issues could cause low DAO ranges, together with:
- Continual intestine irritation (like IBS or leaky intestine)†
- Genetics (some individuals naturally produce much less DAO)†
- Sure medicines, like NSAIDs, antibiotics, and antidepressants†
- Alcohol, which not solely blocks DAO but in addition will increase histamine ranges†
When DAO manufacturing is low or the enzyme is blocked, your physique can’t sustain with histamine from meals—and that’s when signs begin to seem. DAO dietary supplements are designed to fill this hole and assist assist your physique’s skill to course of histamine extra successfully.†
How DAO Dietary supplements Work:
DAO dietary supplements work by giving your physique a brief increase of the enzyme it might be lacking. These dietary supplements usually comprise diamine oxidase sourced from animal tissue (often pig kidney extract), they usually’re designed to be taken proper earlier than meals—particularly those who might comprise high-histamine meals.†
Right here’s the way it works:
If you take a DAO complement earlier than consuming, it sits in your digestive tract and helps break down the histamine present in your meals earlier than it may be absorbed into your bloodstream. This helps scale back the possibilities of triggering signs like complications, flushing, or abdomen points.†
It’s necessary to know that DAO dietary supplements don’t decrease histamine already circulating in your physique—they solely work on the histamine from meals that’s being digested within the second. That’s why timing is vital. When you take a DAO complement after consuming, it possible received’t be as efficient.†
Whereas DAO dietary supplements don’t treatment histamine intolerance, they will act as a useful assist device, particularly should you’re coping with occasional reactions or want just a little buffer when consuming out or touring.†
Who May Profit:
DAO dietary supplements aren’t for everybody, however for the appropriate individual, they will make an enormous distinction. When you’ve been coping with recurring, unexplained signs after consuming sure meals, a DAO complement might assist handle these reactions—particularly should you suspect histamine is the set off.†
You would possibly profit from a DAO complement should you:
- React to high-histamine meals like aged cheese, purple wine, fermented meals, or cured meats†
- Expertise signs like complications, pores and skin flushing, a runny nostril, or digestive discomfort after meals†
- Have a identified DAO deficiency or persistent intestine situations like IBS, SIBO, or leaky intestine†
- Take medicines that intrude with DAO exercise (resembling NSAIDs, antibiotics, or antidepressants)†
- Want short-term assist whereas touring or consuming meals outdoors your standard low-histamine weight-reduction plan†
It’s price noting: DAO dietary supplements don’t deal with the underlying reason behind histamine intolerance—they’re a device to handle signs. Lengthy-term assist may embody intestine therapeutic, dietary adjustments, and figuring out different potential triggers. However should you want quick, meal-by-meal assist, DAO is usually a helpful addition to your routine.†
What to Look For:
Not all DAO dietary supplements are created equal, and because you’re counting on them to assist handle signs, high quality actually issues. Listed here are a couple of key issues to verify earlier than selecting a DAO complement:
Supply of DAO
Only DAO dietary supplements have historically been derived from porcine (pig) kidney extract, which carefully resembles the enzyme your physique naturally produces. Nevertheless, plant-based DAO sourced from pea sprouts has emerged as a viable different, providing related histamine-degrading exercise.†
When you’re vegetarian or want plant-based merchandise, search for choices that particularly checklist Diamine Oxidase (DAO) from plant sources—some normal intestine well being dietary supplements could also be marketed for histamine assist however don’t comprise the energetic DAO enzyme. All the time verify the label to make sure you’re getting a real DAO complement.†
Enzyme Exercise (Measured in HDU)
Search for merchandise that clearly state the HDU (Histamine Degrading Items) on the label. Increased HDU often means extra enzymatic exercise. A typical dosage vary is 10,000–20,000 HDU per serving.†
Clear Formulation
Since individuals with histamine intolerance are sometimes delicate to components, select a product that’s freed from pointless fillers, synthetic colours, preservatives, or elements which may set off reactions (like gluten, soy, or lactose).†
Correct Supply Format
Capsules are the most typical and are often taken 15–half-hour earlier than consuming. Be certain the product is meant to be used with meals, not as a day by day multivitamin.†
Discovering the appropriate DAO complement would possibly take just a little trial and error, however beginning with a clear, correctly dosed method offers you the most effective likelihood at getting actual reduction.
Different Methods to Assist Histamine Steadiness:
Whereas DAO dietary supplements may help handle histamine from meals, they’re only one a part of the larger image. If histamine intolerance is affecting your day by day life, take into account these further methods to assist steadiness and scale back signs:
Observe a Low-Histamine Weight loss program
Keep away from or restrict high-histamine meals like:
- Aged cheeses and cured meats†
- Fermented meals (sauerkraut, kombucha, soy sauce)†
- Alcohol, particularly purple wine and beer†
- Leftovers (histamine will increase as meals sits). Sticking to recent, minimally processed meals could make a noticeable distinction.†
Assist Intestine Well being
A wholesome intestine lining helps regulate histamine and DAO manufacturing. Concentrate on:
- Probiotics (however be selective—some strains might enhance histamine)†
- Digestive enzymes†
- Anti-inflammatory meals (like omega-3s and bone broth)†
Keep away from DAO Blockers
Sure medicines and substances can block DAO exercise, together with:
- NSAIDs (like ibuprofen)†
- Antidepressants (particularly MAO inhibitors)†
- Alcohol†
- Power drinks or inexperienced tea extract (in massive quantities)†
- If potential, work with a healthcare supplier to regulate any medicines which may be contributing.†
Cut back Histamine Triggers in Your Atmosphere
Non-food sources may also contribute to histamine buildup:
- Pollen and mould†
- Pet dander†
- Stress (sure, it may increase histamine ranges too!)†
Managing histamine intolerance usually requires a multi-angle method. DAO dietary supplements may help with food-related signs, however constructing habits that assist your total histamine steadiness offers you a stronger basis for long-term reduction.
The place To Purchase?
When you’re exploring methods to assist your physique’s skill to handle dietary histamine, take into account including DAO dietary supplements to your routine. Two respected choices can be found:
1. Life Extension Food Sensitivity Relief with Diamine Oxidase (DAO)
This complement contains a plant-based DAO enzyme sourced from pea sprouts, designed to assist within the breakdown of histamine-rich meals. It’s formulated to assist relieve occasional non-allergy digestive discomfort related to dietary histamine sensitivity.†
Key Options:
-
Plant-based DAO from pea sprouts†
-
Helps digestion of histamine-rich meals like cured meats and aged cheeses†
-
Vegetarian, gluten-free, and non-GMO†
You should purchase this product straight from SameDaySupplements.com!
2. Solaray DAO Enzyme
Solaray’s DAO Enzyme complement delivers 4.2 mg of diamine oxidase per serving, supplying 60,000 histamine degradation items (HDUs). It’s designed to assist the physique metabolize histamine from meals.†
Key Options:
Each dietary supplements are formulated to assist the breakdown of dietary histamine, doubtlessly assuaging occasional digestive discomfort. As all the time, seek the advice of with a healthcare skilled earlier than including new dietary supplements to your routine.†
Wrapping Up!
This marks the top of our weblog on DAO Dietary supplements for histamine intolerance. Thanks for studying! And as all the time, if there’s something that isn’t clear, one other query you may need, or if in case you have one other thought for a weblog, electronic mail us!
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Warnings And Aspect Results:
Not supposed to be used by individuals below 18. In case you are pregnant, nursing, taking any medicines, or have any medical situations, seek the advice of your physician earlier than use. Discontinue use and seek the advice of your physician if any hostile reactions happen.
Disclaimer:
†Please notice the intention of the knowledge supplied is for reference solely. Moreover, we’re under no circumstances offering medical recommendation or instruction. As a substitute, the knowledge supplied on this information/weblog makes use of anecdotal info and accessible research/opinions. Whereas we purpose to keep up and show correct info, we are able to’t assure it represents the most recent product formulation or info. Due to this fact, please go to the producer’s web site if in case you have any considerations. Additionally, the knowledge above doesn’t symbolize our views right here at Similar Day Dietary supplements. As a substitute, these are the producers’ and customers’ views and knowledge. Moreover, the Meals and Drug Administration has not evaluated these statements. Lastly, these merchandise purpose to not diagnose, deal with, treatment, or stop illness or sickness.