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Barrier dysfunction in nasal epithelium contributes to persistent inflammation in long COVID

Lengthy COVID (LC) is characterised by persistent signs related to persistent irritation and immune dysregulation, however the native tissue mechanisms driving these processes stay poorly understood. Provided that the nasal epithelium is the first entry and an infection web site for SARS-CoV-2, we aimed to research its position in LC and its potential contribution to systemic immune activation.

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