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Atypical Haemolytic Uraemic Syndrome

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The Haemolytic Uremic Syndromes (HUS) are a heterogeneous group of circumstances with differing underlying pathophysiology. These all outcome within the pathological options of thrombotic microangiopathy (TMA) which causes endothelial injury and organ damage. TMAs manifest with a microangiopathic haemolytic anaemia, thrombocytopenia and generally acute kidney damage. The previous twenty years have revealed lots of the immunological, metabolic, ribosomal, cell signalling and clotting pathways answerable for illness.

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