Antigen-Specific Immune Responses and Microbiota Interactions in Skin: Insights into Autoimmune Skin Diseases and

The pores and skin performs a significant function in serving as a bodily and immunological barrier in opposition to exterior insults whereas orchestrating advanced immune responses. Autoimmune pores and skin ailments together with pemphigus, vitiligo, and alopecia areata, illustrate the intricate interaction between antigen-specific immunity and tissue-specific pathologies. Pemphigus serves as a mannequin to know the dynamics of peripheral immune tolerance and the interaction between humoral and mobile autoimmunity, emphasizing the function of regulatory T cells in controlling autoreactive responses.

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