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Allergic Fungal Rhinosinusitis Linked to Other Hyper-IgE Syndromes Through Defective Th17 Responses

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In a gene expression evaluation evaluating sinus mucosa from allergic fungal rhinosinusitis (AFRS) to that from non-AFRS continual rhinosinusitis with nasal polyp (CRSwNP) topics, the antimicrobial peptide (AMP), histatin 1 (HTN1), was discovered to be probably the most differentially down-regulated gene in AFRS.

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