Aberrant follicular regulatory T cells associate with immunoglobulin hyperproduction in nasal polyps with ectopic lymphoid tissues

Continual rhinosinusitis with nasal polyps (CRSwNP) is a situation characterised by persistent irritation of the sinonasal mucosa with outgrowth of polyps.1,2 It stays a big well being downside with a substantial socioeconomic burden and impacts the event and prognosis of different airway ailments, resembling persistent obstructive pulmonary illness and bronchial asthma.2 Present remedy approaches for CRSwNP sometimes contain nonspecific suppression of irritation, endoscopic sinus surgical procedure, and biologics focusing on sort 2 responses.

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