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Nasal gene expression shows a distinct signature in T2-high asthma but not in T2-low disease

T2-low bronchial asthma is outlined by low ranges of sort 2 irritation and is related to resistance to inhaled corticosteroids. Its molecular mechanisms are principally unknown, and therapy choices are restricted. We beforehand confirmed that nasal brush transcriptomes differ between bronchial asthma and controls, reflecting disease-relevant biology.

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