microRNA-mediated allergic angiogenesis and inflammation evident in a preliminary study of the tears of patients with ocular allergy

MicroRNAs (miRNAs) regulate mRNA and protein expression by way of inhibition of translation. miRNAs alter inflammatory biopathways occurring in response to allergenic stimuli (eg, pollen, animal dander, or mud mites) throughout an ocular allergy (OA) flare-up. OA flare-ups are characterised by localized itching, redness, tearing, and irritation. miRNA biomarkers have been explored within the tears of sufferers with ocular inflammatory problems as a result of direct publicity of the ocular floor to environmental allergens.

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