Off-schedule patient-reported outcomes in adults with asthma may influence research results

In scientific analysis, patient-reported outcomes (PROs) corresponding to dyspnea, wheeze, high quality of life, or ache are time-varying.1 Deviation from specified schedules is common1,2 however not usually reported. Delayed or fully missed assessments may lead to responses that differ from responses collected at scheduled occasions. Individuals may have bronchial asthma exacerbations after scheduled reporting occasions regardless that they have been properly when assortment of knowledge on signs was meant. Motivated by our expertise in an ongoing examine, we examined the frequency of and causes for off-schedule PROs.

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