We learn with nice curiosity the article by Knight and Sepiashvili on the challenges of cytokine testing for medical use.1 We acknowledge that Paradigm and Views articles are meant to stimulate dialogue reasonably than present an exhaustive literature evaluate. Nevertheless, we imagine that some key nuances ought to be added to this text. Particularly, we want to (1) develop on the restrictions listed by Knight and Sepiashvili1 as obstacles to implementing these assays, and (2) pragmatically talk about their potential medical utility.
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