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Clinical Response and Corresponding Blood Transcriptome Pathways Pre- And Post-Treatment Of Hereditary Angioedema Prodromes Compared To Active Swelling Attacks
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Roughly 85% Hereditary angioedema (HAE) assaults are related to prodromal signs. We investigated the scientific impact of treating HAE-C1 inhibitor (HAE-C1INH) Kind 1 sufferers with Conestat Alfa® (recombinant human C1-INH) throughout their prodrome versus an energetic swelling episode and related modifications in blood transcriptomic genes and pathways pre- vs. post-treatment.
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