Newborn screening for SCID and severe T lymphocytopenia in Europe

Initiation of new child screening (NBS) packages in Europe dates again to the Nineteen Sixties. One of the latest expansions of NBS packages was the addition of extreme mixed immunodeficiency (SCID) based mostly on detection of T-cell receptor excision circles (TRECs). On this overview, we current an summary of the present state of affairs in Europe. To keep away from a biased overview based mostly on solely printed outcomes, a 37-item survey on TREC-based NBS was despatched to representatives of 46 European international locations. With a response charge of 83%, we collected knowledge of 38 international locations.

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