Continual rhinosinusitis with nasal polyps (CRSwNP) is a power inflammatory illness of the sinonasal mucosa and is characterised by eosinophilic irritation. Nevertheless, the precise roles of eosinophils in CRSwNP are nonetheless largely unclear. Single cell gene expression evaluation of eosinophils in people by single cell RNA sequencing (scRNA-seq) has met technical boundaries, and lots of research have did not detect the appreciable numbers of eosinophils current in nasal polyps (NPs) from sufferers with CRSwNP by scRNA-seq.
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