Protein Barcodes and Next-Generation Protein Sequencing™

Proteins possess numerous conformations, some pivotal in illness pathology. Protein misfolding and aggregation are linked to neurodegenerative situations like Alzheimer’s, Parkinson’s, and Huntington’s illness, and non-neurological illnesses comparable to cataracts, sure atherosclerosis kinds, short-chain amyloidosis, and most cancers. A greater understanding of the poisonous results and clearance of misfolded proteins could reveal novel methods for the prevention and remedy of many illnesses.

Combining Subsequent-Technology Protein Sequencing™ with protein barcoding allows high-throughput mapping of non-native conformations, unattainable by means of crystallization, connecting them to phenotypic results—an arduous process with typical strategies.

Obtain the case research “Use of Protein Barcodes and Subsequent-Technology Protein Sequencing™ for Excessive-Throughput Mapping of Protein Conformations and Their Phenotypic Results” to discover how protein barcoding enhances the understanding of the poisonous results and clearance of misfolded proteins, aiding within the comprehension of illness mechanisms.