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Wechsler et al (Am J Respir Crit Care Med 2024;209:262-72; https://doi.org/10.1164/rccm.202305-0808OC) examined the connection between kind 2 inflammation-associated comorbidities and the effectiveness of biologic brokers in a cohort research involving over 1,700 grownup sufferers with extreme bronchial asthma. Exacerbation price, lung operate, symptom management, and long-term every day oral corticosteroid use had been improved with biologic remedy whatever the presence of kind 2 comorbid circumstances. Notably, higher enhancements in exacerbation price, lung operate, and symptom management had been noticed in sufferers with persistent rhinosinusitis with or with out nasal polyps or with nasal polyps alone.

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