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Engineering therapeutic monoclonal antibodies

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Using human antibodies as biologic therapeutics has revolutionized affected person care all through fields of medication. As our understanding of the various roles antibodies play inside our pure immune responses continues to advance, so will the variety of therapeutic indications for which an mAb will likely be developed. The nice breadth of perform, lengthy half-life, and modular construction permit for almost limitless therapeutic prospects. Human antibodies will be rationally engineered to reinforce their desired immune capabilities and remove those who might end in negative effects.

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