Epithelial-neuronal-immune cell interactions: implications for immunity, inflammation, and tissue homeostasis at mucosal sites

The epithelial lining of the respiratory tract and gut gives a important bodily barrier to guard host tissues in opposition to environmental insults together with dietary antigens, allergens, chemical compounds, and microorganisms. As well as, specialised epithelial cells immediately talk with hematopoietic and neuronal cells. These epithelial-immune and epithelial-neuronal interactions management host immune responses and have necessary implications for inflammatory situations related to defects within the epithelial barrier, together with bronchial asthma, allergy, and inflammatory bowel ailments (IBD).

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