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Epithelial overexpression of IL-33 induces eosinophilic esophagitis dependent on IL-13

Eosinophilic esophagitis (EoE) is an more and more frequent inflammatory situation of the esophagus; nonetheless, the underlying immunologic mechanisms stay poorly understood. The epithelium-derived cytokine IL-33 is related to sort 2 immune responses and elevated in esophageal biopsies from EoE topics.

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