Cannabinoid receptor 2 as a regulator of inflammation induced by oleoylethanolamide in eosinophilic asthma

Bronchial asthma is a heterogeneous illness encompassing totally different scientific phenotypes relying on the presence of atopy, weight problems, or age at onset of bronchial asthma.1 Along with various scientific phenotypes, bronchial asthma can be a biologically heterogeneous illness, with distinct irritation patterns together with sort 2 (T2)-high and T2-low bronchial asthma. In T2-high bronchial asthma, T2 cytokines, together with IL-4, IL-5, and IL-13, act as a major activator and regulator of B lymphocytes, TH2 lymphocytes, and eosinophils. It’s reported that round 50% to 90% of individuals with bronchial asthma have T2 irritation.

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