Booster doses of COVID-19 vaccine enhance neutralization efficiency against XBB.1.5

The swift emergence of XBB.1.5 highlights the speedy mutation dynamics of extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Renewed urgency led to growth of bivalent vaccines to counter the potential menace of XBB.1.5. Contemplating that the majority people obtained earlier variations of coronavirus illness 2019 (COVID-19) vaccine, the effectiveness of these variations in defending towards XBB.1.5 stays unsure. We assessed whether or not obtainable booster vaccines induce neutralizing antibodies towards XBB.1.5 and the Wuhan wild-type pressure and whether or not bivalent vaccines (BVs) towards BA.4/5 are superior to monovalent vaccines (MVs) in inducing XBB.1.5-neutralizing antibodies.

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